For research use only. Products are supplied strictly for laboratory and research purposes and are not intended for human consumption.
- Batch tested
- COA available
- Research use only
Matrix research
GHK-Cu
Naturally occurring copper-binding tripeptide referenced in collagen synthesis and extracellular matrix remodelling literature.
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Verified test results
Every batch, independently documented.
Review the testing information and certificate available for the selected product batch.
ILS Laboratories
Certificate of Analysis
99.61%
Purity
- Lot
- APGHKC01
- Tested
- 12 Jun 2026
- Label claim
- 50mg vial
- Measured
- 50mg vial
Full QC panel
8 results reported
Appearance
Visual
White lyophilised cake
PassPurity
HPLC-UV, 214nm
99.61%
PassNet peptide content
Nitrogen determination
Conforms
PassIdentity
LC-MS (ESI+)
Confirmed
PassBacterial endotoxin
LAL kinetic chromogenic
< 0.05 EU/mg
PassHeavy metals
ICP-MS
Not detected
PassSterility
USP <71>
No growth
PassResidual solvents
GC headspace
Within limits
Pass
Every batch on record
View available certificates for previous product lots.
Product information
Research Detail
Research-grade GHK-Cu peptide. A copper-binding tripeptide complex supplied as lyophilized powder for in vitro research. Third-party tested with Certificate of Analysis available.
What is GHK-Cu?
GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper-binding peptide complex studied for its role in cellular communication, extracellular matrix remodelling, tissue-response signalling, and gene-expression regulation.
GHK is a tripeptide made from glycine, histidine, and lysine. When complexed with copper, it forms GHK-Cu — a peptide-copper complex widely examined in laboratory and preclinical research for its relationship with collagen regulation, fibroblast activity, angiogenic signalling, antioxidant-response pathways, and inflammatory signalling.
Because of its connection to copper transport and repair signalling, GHK-Cu remains a major research compound in regenerative biology, dermatological research, connective-tissue models, and peptide-mediated cellular signalling.
Compound Profile
- Common Name
- Copper Tripeptide-1
- Sequence
- Gly-His-Lys (GHK)
- Molecular Weight
- 401.91 g/mol
- Molecular Formula
- C14H22CuN6O4
- CAS Number
- 89030-95-5
- Peptide Type
- Copper-binding tripeptide complex
- Research Category
- Collagen regulation, ECM remodelling, angiogenic signalling
- Purity
- ≥99% (HPLC verified)
Key Areas of Investigation
GHK-Cu has been studied across dermatological, structural, cellular, vascular, and systemic research models. Published research discusses its role in tissue remodelling, copper-dependent signalling, and extracellular matrix regulation.
These findings support GHK-Cu as a versatile research compound for studying skin biology, regenerative signalling, and cellular repair mechanisms, but they do not establish approved therapeutic use.
- Structural Research: Collagen synthesis, elastin regulation, decorin expression, extracellular matrix organisation, and connective-tissue remodelling.
- Dermatological Research: Skin physiology, wound-response models, epithelial remodelling, hair-follicle signalling, and dermal fibroblast activity.
- Cellular Research: Fibroblast proliferation, cell migration, growth-factor expression, antioxidant-response pathways, and cellular repair signalling.
- Vascular Research: Angiogenic signalling, endothelial response, vascular remodelling, and growth-factor-related pathways.
- Inflammatory Research: Inflammatory pathway modulation, oxidative-stress response, tissue-protection models, and matrix metalloproteinase regulation.
Scientific references
- Pickart L. & Thaler M.M. (1973)
- Freedman J.H. et al. (1982)
- Wegrowski Y. et al. (1992)
- Simé️on A. et al. (2000)
- McCormack M.C. et al. (2001)
- Pollard J.D. et al. (2005)
- Pickart L. et al. (2015)
- Pickart L. & Margolina A. (2018)
- Dou Y. et al. (2020)
- Mortazavi S.M. et al. (2024)
Technical specifications
Compound Information
Molecular profile
What is GHK-Cu?
GHK-Cu is a naturally occurring copper-binding tripeptide, extensively referenced in collagen and extracellular matrix literature. Supplied as a lyophilised powder with a characteristic blue tint from the copper complex.
- Chemical class
- Copper tripeptide complex
- CAS number
- 89030-95-5
- Molecular weight
- 402.9 g/mol
- Amino acids
- 3
- Formula
- C14H22CuN6O4
- Sequence
- GHK · Cu(II)
Storage requirements
Stability information
- −20°C
Lyophilised powder
Sealed, protected from light. Stable 24 months.
- 2–8°C
Reconstituted
Use within 28 days of reconstitution.
- Ambient
In transit
Store sealed at 2–8°C, protected from light
Store sealed at 2–8°C, protected from light
Important research notice
Not for human, veterinary, or food use.
These products are supplied exclusively for laboratory and research purposes and are not intended for human consumption, diagnosis, treatment, cure, or prevention of disease.
Product information and research references are provided for educational and laboratory reference purposes.